1-Acetyl-5-bromo-4-chloro-1H-indol-3-yl acetate

1-Acetyl-5-bromo-4-chloro-1H-indol-3-yl acetate - Names and Identifiers

Name	5-bromo-4-chloroindoxyl-1,3-diacetate
Synonyms	5-bromo-4-chloroindoxyl-1,3-diacetate 5-BROMO-4-CHLOROINDOXYL-1,3-DIACETATE 5-BROMO-4-CHLORO-3-INDOLYL-1,3-DIACETATE 3 ACETOXY-1-ACETYL-5-BROMO-4-CHLOROINDOLE N-ACETYL-5-BROMO-4-CHLOROINDOL-3-YL ACETATE 1-ACETYL-5-BROMO-4-CHLORO-1H-INDOL-3-YL ACETATE 1-Acetyl-5-bromo-4-chloro-1H-indol-3-yl acetate 1-acetyl-5-bromo-4-chloro-1h-indol-3-oacetate(ester) ACETIC ACID-(1-ACETYL-5-BROMO-4-CHLORO-1H-INDOL-3-YL) ESTER
CAS	3030-06-6
EINECS	221-200-6
InChI	InChI=1/C12H9BrClNO3/c1-6(16)15-5-10(18-7(2)17)11-9(15)4-3-8(13)12(11)14/h3-5H,1-2H3

1-Acetyl-5-bromo-4-chloro-1H-indol-3-yl acetate - Physico-chemical Properties

Molecular Formula	C12H9BrClNO3
Molar Mass	330.56
Density	1?+-.0.1 g/cm3(Predicted)
Melting Point	165-168 °C (lit.)
Boling Point	429.5±40.0 °C(Predicted)
Flash Point	213.5°C
Solubility	Chloroform (Slightly), DMSO (Sparingly), Ethyl Acetate (Slightly), Methanol (Ver
Vapor Presure	1.4E-07mmHg at 25°C
Appearance	Powder
Color	Pale Yellow to Dark Yellow
BRN	270885
Storage Condition	2-8°C
Stability	Moisture, Temperature, Light sensitive
Refractive Index	1.631
MDL	MFCD00040632
Physical and Chemical Properties	Melting point 164-168°C
Use	This product is for scientific research only and shall not be used for other purposes.

1-Acetyl-5-bromo-4-chloro-1H-indol-3-yl acetate - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
UN IDs	UN 2811
WGK Germany	3
FLUKA BRAND F CODES	8-10

1-Acetyl-5-bromo-4-chloro-1H-indol-3-yl acetate - Introduction

5-bromo-4-choroindoxyl-1, 3-diacetate is a chemical substance with the chemical formula C14H11BrClNO4. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: A white to light yellow solid
-Melting point: approximately 110 ° C to 112 ° C
-Solubility: Soluble in organic solvents such as methanol, dichloromethane
-Stability: stable at regular temperatures, but avoid exposure to sunlight

Use:
5-bromo-4-chloroindoxyl-1,3-diacetate is a chromogenic substance for chemical analysis. It can be hydrolyzed to form derivatives of indole compounds containing pyrrole ring. This color reaction is widely used in the determination of enzyme activity, microbial detection of bacterial culture medium and histological research.

Method:
The preparation of 5-bromo-4-choroindoxyl-1, 3-diacetate can be carried out by the following steps:
1. Indole reacts with acetic anhydride to form 1-acetoindole.
2. In the environment to add bromine and chlorine, making the acetyl indole halogenated reaction to generate 1-acetyl -5-bromo -4-chloro indole.
3. React the reaction product with acetic acid anhydride to generate 5-bromo-4-chloroindoxyl-1,3-diacetate.

Safety Information:
5-bromo-4-chloroindoxyl-1,3-diacetate is a chemical, and the following safety precautions should be paid attention:
-Use with appropriate personal protective equipment, such as lab gloves and goggles.
-Avoid inhaling its dust or gas, and operate in a well-ventilated place.
-avoid contact with skin and eyes, such as contact, should immediately rinse with plenty of water.
-Avoid ingestion. If ingested, seek medical attention immediately.

Last Update：2024-04-10 22:29:15